Research

Cobbett Lab

Topic 3: Glutathione is essential for growth and development and plays an important role in responses to heavy metal stress.

We have previously shown that glutathione-deficient mutants are cadmium-sensitive. More severe glutathione-deficient mutants are either affected in root development or fail to develop as embryos. Work in this area is aimed at exploring the roles of glutathione in development and mechanisms of glutathione transport.

Figure 1. 10 day rml1 homozygous and WT seedlings germinated on minimum media.

Figure 2. Immature seeds from a GCS T-DNA heterozygous plant.

Topic 1: Heavy Metal Transporting P-type ATPases are essential for zinc homeostasis

Topic 2: Major Facilitator Superfamily transporters have an unexpected role in zinc homeostasis

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